Preheat the oven to 350 degrees. In a medium bowl, whisk together the flour, baking soda, baking powder, cinnamon, pumpkin pie spice, and salt.
In a separate larger bowl, stir together the pumpkin, oil, milk, eggs, granulated sugar, brown sugar, and vanilla until well combined.
Pour the dry ingredients into the wet. Fold until just combined.
In a separate bowl, with an electric mixer, beat on medium high speed the cream cheese, egg, and sugar together until well combined.
Prepare a 9 x 5 loaf pan (a 8.5 x 4 is too small) by spraying it lightly with oil and lining it with parchment paper.
Spoon about half of the pumpkin batter into the pan and spread it into an even layer.
Spoon all of the cream cheese mixture on top of the batter and spread it gently into an even layer.
Pour the remaining batter on top of the cream cheese layer and spread it into an even layer.
Sprinkle some pumpkin seeds on top.
Bake for 72-80 minutes or until a toothpick comes out mostly clean. Cover with foil about halfway through so the top does not brown too much. The loaf will continue to cook as it cools. Cool on a wire rack completely before slicing.